CABT-BL3313

antibody from Creative Diagnostics

Targeting: SLC25A19 DNC, MCPHA, MUP1, TPC

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-BL3313

Provider

Creative Diagnostics

Product name

Anti-Slc25a19 polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

Reactivity

Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.