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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Western blot [1]
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- Product number
- 639301 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#639301, RRID:AB_2230595
- Product name
- Purified anti-DDX3
- Antibody type
- Polyclonal
- Antigen
- DDX3
- Description
- DDX3 is a member of DEAD box family which is RNA helicases characterized by a conserved motif of D-E-A-D (Asp-Glu-Ala-Asp) amino acid sequence. DDX3 is implicated in many cellular processes, such as altering RNA secondary structure and , export of HIV-1 viral transcripts, HCV viral RNA replication. DDX3 has potential importance in both cancer, and viral infection as well as its roles in numerous cellular processes, such as embryogenesis, spermatogenesis and cellular growth and proliferation.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 25 µl
- Storage
- Upon receipt, store frozen at -20° C.
Submitted references In vitro epsilon RNA-dependent protein priming activity of human hepatitis B virus polymerase.
Jones SA, Boregowda R, Spratt TE, Hu J
Journal of virology 2012 May;86(9):5134-50
Journal of virology 2012 May;86(9):5134-50
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- HeLa cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with polyclonal anti-DDX3 antibody (clone Poly6393). Proteins were visualized using a donkey anti-rabbit IgG conjugated to HRP and chemiluminescence detection.
- Conjugate
- Unconjugated
