Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS6125 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- RNASE13 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human RNASE13.
- Description
- Ribonucleases are ubiquitous enzymes involved in RNA metabolism and are classified in several families on the basis of their structural, catalytic and biological properties. RNase 13 (ribonuclease, RNase A family, 13), is a 156 amino acid secreted protein encoded by a gene that maps to human chromosome 14q11.2. Chromosome 14 houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder Ï«1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of RNASE13 pAb in extracts from mouse liver and testis tissues.