FNab10051

antibody from FineTest Biotech

Targeting: DDR1 CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6

Provider product page for FNab10051

Western blot

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [0]
Comments [0]
Validations [0]

Submit

Product number: FNab10051 - Provider product page
Provider: FineTest Biotech
Product name: DDR1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing(By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
Reactivity: Human, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: discoidin domain receptor tyrosine kinase 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

DDR1 protein structure - FNab10051 shown in red.