FNab03990

antibody from FineTest Biotech

Targeting: HP

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab03990 - Provider product page
Provider: FineTest Biotech
Product name: HP antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
Reactivity: Human, Porcine
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: haptoglobin
Epitope: IgG2a
Isotype: IgG
Antibody clone number: 7C8
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

HP protein structure - FNab03990 shown in red.