Tissue expression
Cell line expression
Protein structure
MGME1
Mitochondrial genome maintenance exonuclease 1bA504H3.4, C20orf72, DDK1
The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
Top validated antibodies |
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Proteintech Group | ![]() |
4 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
3 references | Polyclonal |
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Atlas Antibodies | ![]() |
7 references | Polyclonal |
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Acris Antibodies GmbH | ![]() |
Polyclonal |
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