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- Immunohistochemistry [5]
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- Product number
- NBP1-91169 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-91169, RRID:AB_11008565
- Product name
- Rabbit Polyclonal CHCHD10 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human CHCHD10 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Neuropathologic description of CHCHD10 mutated amyotrophic lateral sclerosis.
Novel mutation in TNPO3 causes congenital limb-girdle myopathy with slow progression.
A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement.
Keith JL, Swinkin E, Gao A, Alminawi S, Zhang M, McGoldrick P, McKeever P, Robertson J, Rogaeva E, Zinman L
Neurology. Genetics 2020 Feb;6(1):e394
Neurology. Genetics 2020 Feb;6(1):e394
Novel mutation in TNPO3 causes congenital limb-girdle myopathy with slow progression.
Vihola A, Palmio J, Danielsson O, Penttilä S, Louiselle D, Pittman S, Weihl C, Udd B
Neurology. Genetics 2019 Jun;5(3):e337
Neurology. Genetics 2019 Jun;5(3):e337
A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement.
Bannwarth S, Ait-El-Mkadem S, Chaussenot A, Genin EC, Lacas-Gervais S, Fragaki K, Berg-Alonso L, Kageyama Y, Serre V, Moore DG, Verschueren A, Rouzier C, Le Ber I, Augé G, Cochaud C, Lespinasse F, N'Guyen K, de Septenville A, Brice A, Yu-Wai-Man P, Sesaki H, Pouget J, Paquis-Flucklinger V
Brain : a journal of neurology 2014 Aug;137(Pt 8):2329-45
Brain : a journal of neurology 2014 Aug;137(Pt 8):2329-45
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CHCHD10 Antibody [NBP1-91169] - Analysis in human cell lines PC-3 and U-251MG using anti-CHCHD10 antibody. Corresponding CHCHD10 RNA-seq data are presented for the same cell lines. Loading control: anti-HSP90B1.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CHCHD10 Antibody [NBP1-91169] - Analysis in human skeletal muscle and skin tissues. Corresponding CHCHD10 RNA-seq data are presented for the same tissues.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CHCHD10 Antibody [NBP1-91169] - Staining of human skin shows no positivity in squamous epithelial cells as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CHCHD10 Antibody [NBP1-91169] - Staining of human liver shows moderate granular cytoplasmic positivity in hepatocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CHCHD10 Antibody [NBP1-91169] - Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CHCHD10 Antibody [NBP1-91169] - Staining of human colon shows moderate granular cytoplasmic positivity in glandular cells.
