NUDT14

The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules. This enzyme contains a Nudix hydrolase domain and is a UDPG pyrophosphatase that hydrolyzes UDPG to produce glucose 1-phosphate and UMP. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

Description

Nudix hydrolase 14

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli, Microtubules

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

14 (105172938 - 105181323)

Ensembl ID

ENSG00000183828  (ver. 103.38)

Orthologs

Mouse Nudt14: ENSMUSG00000002804

UniProt

O95848

neXtProt

NX_O95848

Human splice variants
Mouse splice variants

Protein structure