BS3888

antibody from Bioworld Technology, Inc
Targeting: NCR3 1C7, CD337, LY117, NKp30
Provider product page for BS3888

Antibody data

Product number
BS3888 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3888, RRID:AB_1914283
Product name
NKp30 (L134) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 111-160 of Human NKp30.
Description
The p30-15 monoclonal antibody recognizes CD337 also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3. NKp30 is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp30 has an apparent molecular weight of 30 kD and six isoforms are produced by alternative splicing. NKp30 is expressed on IL-2 activated NK cells and NK cell lines as well as some in vitro activated ÎÛ/Ñ´ T cells. NKp30 enhances NK cell triggering and cytolysis of tumor targets and other target cells deficient in MHC class I molecules. NKp30 has been shown to associate with CD59 and TCRšø. The p30-15 antibody against human NKp30 has been shown to be useful for flow cytometry, stimulation of human NK cells via NKp30 in a redirected lysis assay, and blocking of NKp30 function in solution.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NCR3 protein structure - BS3888 shown in red.