325208

antibody from BioLegend

Targeting: NCR3 1C7, CD337, LY117, NKp30

Antibody data

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Validation data

Product number: 325208 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#325208, RRID:AB_756112
Product name: PE anti-human CD337 (NKp30)
Antibody type: Monoclonal
Antigen: Recombinant human NKp30
Description: The p30-15 monoclonal antibody recognizes CD337 also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3. NKp30 is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp30 has an apparent molecular weight of 30 kD and six isoforms are produced by alternative splicing. NKp30 is expressed on resting and activated NK cells. NKp30 enhances NK cell cytolysis of tumor cellts that are deficient in MHC class I molecules. NKp30 has been shown to associate with CD59 and TCRζ. The p30-15 antibody against human NKp30 has been shown to be useful for flow cytometry, stimulation of human NK cells via NKp30 in a redirected lysis assay, and blocking of NKp30 function in solution.
Reactivity: Human
Host: Mouse
Conjugate: Yellow dye
Isotype: IgG
Vial size: 100 tests
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

NCR3 protein structure - 325208 shown in red.