ANAPC13

This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008]

Description

Anaphase promoting complex subunit 13

Tissue specificity

Low tissue specificity

Subcell location

Mitochondria, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

3 (134477706 - 134486716)

Ensembl ID

ENSG00000129055  (ver. 103.38)

Orthologs

Mouse Anapc13: ENSMUSG00000035048

UniProt

Q9BS18

neXtProt

NX_Q9BS18

Human splice variants
Mouse splice variants

Protein structure