AF4527

antibody from Novus Biologicals

Targeting: PEAR1 FLJ00193, JEDI, MEGF12

Western blot (Data presented on provider website)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

AF4527

Provider

Novus Biologicals

Product name

Goat Polyclonal PEAR1 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects human PEAR1 in direct ELISAs and Western blots.

Reactivity

Human

Host

Goat

Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

A novel mechanism of sustained platelet αIIbβ3 activation via PEAR1.

Kauskot A, Di Michele M, Loyen S, Freson K, Verhamme P, Hoylaerts MF
Blood 2012 Apr 26;119(17):4056-65

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Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression.

Faraday N, Yanek LR, Yang XP, Mathias R, Herrera-Galeano JE, Suktitipat B, Qayyum R, Johnson AD, Chen MH, Tofler GH, Ruczinski I, Friedman AD, Gylfason A, Thorsteinsdottir U, Bray PF, O'Donnell CJ, Becker DM, Becker LC
Blood 2011 Sep 22;118(12):3367-75

Flow cytometry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Detection of PEAR1 in Human CD41⁺ Platelets by Flow Cytometry. Human CD41⁺ platelets were stained with Human PEAR1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4527, filled histogram) or control antibody (Catalog # AB-108-C, open histogram), followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0108).