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Western blot
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Flow cytometry [1]
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- Product number
- AF4527 - Provider product page
- Provider
- R&D Systems
- Product name
- Human PEAR1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects human PEAR1 in direct ELISAs and Western blots.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
Q5VY43- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references A novel mechanism of sustained platelet αIIbβ3 activation via PEAR1.
Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression.
Kauskot A, Di Michele M, Loyen S, Freson K, Verhamme P, Hoylaerts MF
Blood 2012 Apr 26;119(17):4056-65
Blood 2012 Apr 26;119(17):4056-65
Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression.
Faraday N, Yanek LR, Yang XP, Mathias R, Herrera-Galeano JE, Suktitipat B, Qayyum R, Johnson AD, Chen MH, Tofler GH, Ruczinski I, Friedman AD, Gylfason A, Thorsteinsdottir U, Bray PF, O'Donnell CJ, Becker DM, Becker LC
Blood 2011 Sep 22;118(12):3367-75
Blood 2011 Sep 22;118(12):3367-75
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of PEAR1 in Human CD41+ Platelets by Flow Cytometry. Human CD41+ platelets were stained with Human PEAR1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4527, filled histogram) or control antibody (Catalog # AB-108-C, open histogram), followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0108).
