ARHGAP31

This gene encodes a GTPase-activating protein (GAP). A variety of cellular processes are regulated by Rho GTPases which cycle between an inactive form bound to GDP and an active form bound to GTP. This cycling between inactive and active forms is regulated by guanine nucleotide exchange factors and GAPs. The encoded protein is a GAP shown to regulate two GTPases involved in protein trafficking and cell growth. [provided by RefSeq, Jul 2008]

Description

Rho GTPase activating protein 31

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

3 (119294383 - 119420714)

Ensembl ID

ENSG00000031081  (ver. 103.38)

Orthologs

Mouse Arhgap31: ENSMUSG00000022799

UniProt

Q2M1Z3

neXtProt

NX_Q2M1Z3

Human splice variants
Mouse splice variants

Protein structure