Tissue expression
Cell line expression
Protein structure
POGLUT1
Protein O-glucosyltransferase 19630046K23Rik, C3orf9, hCLP46, KDELCL1, KTELC1, MDS010, MDSRP, MGC32995, Rumi
This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Top validated antibodies |
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Proteintech Group | 24409-1-AP | Polyclonal |
WB
EL
ICC
IHC |
||
Novus Biologicals | NBP1-90311 | 3 references | Polyclonal |
WB
IHC |
|
NovoPro Bioscience Inc. | 112137 | Polyclonal |
WB
EL
ICC
IHC |
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Invitrogen Antibodies | 24409-1-AP | Polyclonal |
WB
ICC
IHC
|
||
FineTest Biotech | FNab04659 | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider