Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-L206RM - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Rabbit Anti-Human IRG1 monoclonal antibody, clone FQS33177
- Antibody type
- Monoclonal
- Description
- IRG1 (Immune-responsive gene 1) is one of the most up-regulated genes in macrophages under proinflammatory conditions. It is also highly expressed in the pregnant uterus during implantation. IRG1 is a cis-aconitate decarboxylase that produces itaconic acid bydecarboxylating cis-aconic acid, an intermediate of the tricarboxylic acid cycle. Itaconic acid is an endogenous inhibitor of succinate dehydrogenase, linking macrophage metabolic rewiring and regulation of inflammation
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- FQS33177
- Vial size
- 100 ul
- Concentration
- Lot specific
- Storage
- Short Term: 2-8°C. Long Term: -20°C. Avoid repeated freezing and thawing.
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