PAAF1

This gene encodes a WD repeat-containing protein involved in regulation of association of proteasome components. During HIV infection, the encoded protein is thought to promote provirus transcription through recruitment of the 19S regulatory complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]

Description

Proteasomal ATPase associated factor 1

Tissue specificity

Tissue enhanced (brain)

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

11 (73876699 - 73931114)

Ensembl ID

ENSG00000175575  (ver. 103.38)

Orthologs

-

UniProt

Q9BRP4

neXtProt

NX_Q9BRP4

Human splice variants

Protein structure