Tissue expression
Cell line expression
Protein structure
FRMD4A
FERM domain containing 4AbA295P9.4, FLJ10210, FRMD4, KIAA1294
This gene encodes a FERM domain-containing protein that regulates epithelial cell polarity. It connects ADP ribosylation factor 6 (ARF6) with the Par protein complex, which regulates the remodeling of adherens junctions and linear actin cable formation during epithelial cell polarization. Polymorphisms in this gene are associated with Alzheimer's disease, and also with nicotine dependence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Top validated antibodies |
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Biorbyt | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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Atlas Antibodies | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
Polyclonal |
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