NLRP9

The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]

Description

NLR family pyrin domain containing 9

Tissue specificity

Not detected

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

19 (55708438 - 55738402)

Ensembl ID

ENSG00000185792  (ver. 103.38)

Orthologs

-

UniProt

Q7RTR0

neXtProt

NX_Q7RTR0

Human splice variants

Protein structure