Tissue expression
Cell line expression
Protein structure
ARHGAP11A
Rho GTPase activating protein 11AKIAA0013
This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb 2019]
Top validated antibodies |
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Atlas Antibodies | HPA040830 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Novus Biologicals | NBP1-93657 | 1 references | Polyclonal |
WB
IHC |
|
Invitrogen Antibodies | PA5-59170 | Polyclonal |
WB
ICC
IHC
|
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antibodies-online | ABIN4281491 | Polyclonal |
WB
ICC
IHC
|
||
Affinity Biosciences | DF4425 | Polyclonal |
WB
EL
ICC
|
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Supportive data in Antibodypedia
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Recommended by provider