TSPAN16

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein might couple to signal transduction pathways and possibly modulate cellular activation and adhesion in haemopoietic and neural tissue. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Description

Tetraspanin 16

Tissue specificity

Tissue enriched (testis)

Subcell location

Plasma membrane

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Kim et al 2014)

Chromosome

19 (11296139 - 11326996)

Ensembl ID

ENSG00000130167  (ver. 103.38)

Orthologs

-

UniProt

Q9UKR8

neXtProt

NX_Q9UKR8

Human splice variants

Protein structure