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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB12320 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12320, RRID:AB_10552110
- Product name
- CUL4B polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of CUL4B.
- Isotype
- IgG
- Storage
- Store at -20°C on dry atmosphere.After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.Aliquot to avoid repeated freezing and thawing.
Submitted references Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation.
Dioxin receptor is a ligand-dependent E3 ubiquitin ligase.
Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor.
Zou Y, Liu Q, Chen B, Zhang X, Guo C, Zhou H, Li J, Gao G, Guo Y, Yan C, Wei J, Shao C, Gong Y
American journal of human genetics 2007 Mar;80(3):561-6
American journal of human genetics 2007 Mar;80(3):561-6
Dioxin receptor is a ligand-dependent E3 ubiquitin ligase.
Ohtake F, Baba A, Takada I, Okada M, Iwasaki K, Miki H, Takahashi S, Kouzmenko A, Nohara K, Chiba T, Fujii-Kuriyama Y, Kato S
Nature 2007 Mar 29;446(7135):562-6
Nature 2007 Mar 29;446(7135):562-6
Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor.
Tarpey PS, Raymond FL, O'Meara S, Edkins S, Teague J, Butler A, Dicks E, Stevens C, Tofts C, Avis T, Barthorpe S, Buck G, Cole J, Gray K, Halliday K, Harrison R, Hills K, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Varian J, West S, Widaa S, Mallya U, Moon J, Luo Y, Holder S, Smithson SF, Hurst JA, Clayton-Smith J, Kerr B, Boyle J, Shaw M, Vandeleur L, Rodriguez J, Slaugh R, Easton DF, Wooster R, Bobrow M, Srivastava AK, Stevenson RE, Schwartz CE, Turner G, Gecz J, Futreal PA, Stratton MR, Partington M
American journal of human genetics 2007 Feb;80(2):345-52
American journal of human genetics 2007 Feb;80(2):345-52
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western Blot analysis of CUL4B expression from cell and tissue extracts with CUL4B polyclonal antibody (Cat # PAB12320).Lane 1 : female zebrafish tissue lysate.Lane 2 : MM453 whole cell lysate.Lane 3 : rat liver tissue lysate.Lane 4 : rat lung tissue lysate.Lane 5 : MCF-7 whole cell lysate.Lane 6 : MM231 whole cell lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical staining of CUL4B on formalin fixed, paraffin embedded zebrafish body with CUL4B polyclonal antibody (Cat # PAB12320).
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
