APR01794G

antibody from Leading Biology

Targeting: FBXL15 Fbl15, FBXO37, MGC11279

Western blot (Recommended by provider)

Antibody Data

Product number

APR01794G

Provider

Leading Biology

Product name

FBXL15 Antibody - N-terminal region

Antibody type

Polyclonal

Description

Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.

Reactivity

Human, Mouse, Rat, Bovine, Canine, Horse, Rabbit

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.