Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS7429 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- GNA11 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human GNA11.
- Description
- Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of Ï«, ÉÇ and ÎÛ subunits and mediate the effects of hormones, neurotransmitters, chemokines and sensory stimuli. To date, over 20 known GÏ« subunits have been classified into four families, GÏ«(s), GÏ«(i/o), GÏ«(q) and GÏ«(12), based on structural and functional similarities (1,2). Phosphorylation of Tyr356 of GÏ«(q)/GÏ«(11) is essential for activation of the G protein, since phenylalanine substitution for Tyr356 changes the interaction of GÏ« with receptors and abolishes ligand-induced IP3 formation (3).
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot analysis of GNA11 polyclonal antibody