ARL14EP

The protein encoded by this gene is an effector protein. It interacts with ADP-ribosylation factor-like 14 [ARL14, also known as ADP-ribosylation factor 7 (ARF7)], beta-actin (ACTB) and actin-based motor protein myosin 1E (MYO1E). ARL14 is a small GTPase; it controls the export of major histocompatibility class II molecules by connecting to the actin network via this effector protein. [provided by RefSeq, Sep 2014]

Description

ADP ribosylation factor like GTPase 14 effector protein

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Vesicles, Focal adhesion sites, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

11 (30323104 - 30338223)

Ensembl ID

ENSG00000152219  (ver. 103.38)

Orthologs

Mouse Arl14ep: ENSMUSG00000027122

UniProt

Q8N8R7

neXtProt

NX_Q8N8R7

Human splice variants
Mouse splice variants

Protein structure