FCGR1B

Three distinct, but closely related classes of receptors that bind the Fc portion of IgG have been identified (Fcgamma RI, II and III). The FcgammaRI family consists of three closely related genes termed A, B, and C. This gene encodes the low affinity FcgammaRIB receptor that may play an important role in humoral immune response. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Description

Fc fragment of IgG receptor Ib

Tissue specificity

Tissue enhanced (epididymis, lymphoid tissue)

Subcell location

Golgi apparatus, Vesicles, Plasma membrane

Predicted location

Intracellular, Membrane

Protein family

FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins

Chromosome

1 (121087345 - 121097161)

Ensembl ID

ENSG00000198019  (ver. 103.38)

Orthologs

-

UniProt

Q92637

neXtProt

NX_Q92637

Human splice variants

Protein structure