Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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- Product number
- AF6294 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Sheep Polyclonal ONECUT2/OC-2 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human ONECUT2/OC-2 in direct ELISAs. In direct ELISAs, approximately 10% cross-reactivity with recombinant human ONECUT1 is observed.
- Reactivity
- Human
- Host
- Sheep
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits.
Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma.
Unique Gene Expression Signatures in the Intestinal Mucosa and Organoids Derived from Germ-Free and Monoassociated Mice.
Rb is required for retinal angiogenesis and lamination.
The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development.
A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells.
Toch M, Harris A, Schakman O, Kondratskaya E, Boulland JL, Dauguet N, Debrulle S, Baudouin C, Hidalgo-Figueroa M, Mu X, Gow A, Glover JC, Tissir F, Clotman F
Scientific reports 2020 Jan 22;10(1):996
Scientific reports 2020 Jan 22;10(1):996
Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma.
Wei R, Ren X, Kong H, Lv Z, Chen Y, Tang Y, Wang Y, Xiao L, Yu T, Hacibekiroglu S, Liang C, Nagy A, Bremner R, Chen D
JCI insight 2019 Nov 14;4(22)
JCI insight 2019 Nov 14;4(22)
Unique Gene Expression Signatures in the Intestinal Mucosa and Organoids Derived from Germ-Free and Monoassociated Mice.
Janeckova L, Kostovcikova K, Svec J, Stastna M, Strnad H, Kolar M, Hudcovic T, Stancikova J, Tureckova J, Baloghova N, Sloncova E, Galuskova K, Tlaskalova-Hogenova H, Korinek V
International journal of molecular sciences 2019 Mar 29;20(7)
International journal of molecular sciences 2019 Mar 29;20(7)
Rb is required for retinal angiogenesis and lamination.
Zhou Y, Wei R, Zhang L, Chen Y, Lu S, Liang C, Wang Y, Xiao L, Zhang J, Bremner R, Chen D
Cell death & disease 2018 Mar 6;9(3):370
Cell death & disease 2018 Mar 6;9(3):370
The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development.
Kabayiza KU, Masgutova G, Harris A, Rucchin V, Jacob B, Clotman F
Frontiers in molecular neuroscience 2017;10:157
Frontiers in molecular neuroscience 2017;10:157
A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells.
Velasco S, Ibrahim MM, Kakumanu A, Garipler G, Aydin B, Al-Sayegh MA, Hirsekorn A, Abdul-Rahman F, Satija R, Ohler U, Mahony S, Mazzoni EO
Cell stem cell 2017 Feb 2;20(2):205-217.e8
Cell stem cell 2017 Feb 2;20(2):205-217.e8
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