GRIN3A

This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity. [provided by RefSeq, Jul 2008]

Description

Glutamate ionotropic receptor NMDA type subunit 3A

Tissue specificity

Tissue enhanced (brain)

Predicted location

Membrane

Protein family

FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Kim et al 2014)

Chromosome

9 (101569352 - 101738647)

Ensembl ID

ENSG00000198785  (ver. 103.38)

Orthologs

Mouse Grin3a: ENSMUSG00000039579

UniProt

Q8TCU5

neXtProt

NX_Q8TCU5

Human splice variants
Mouse splice variants

Protein structure