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Other assayAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Other assay [1]
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- Product number
- MA1-26180 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Cardiac Myosin Heavy Chain Monoclonal Antibody (3-48)
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Description
- This antibody is myosin alpha and beta heavy chain specific. Affinity constants: Human ventricular myosin heavy chains - 3.33 x 108M-1; Human atrial myosin heavy chains - 1.48 x 108M-1; Human skeletal muscle myosin - 1.06 x 108M-1; Canine cardiac myosin heavy chains - 2.06 x 108M-1. This antibody cross-reacts with heavy chains of human myosin isolated from slow skeletal muscle, fast skeletal muscle, eye muscle, and streptococcal M5 peptide. It does not react with human platelets, smooth muscle myosin heavy chains, myosin light chains, myosin fragments circulating in blood of patients with myocardial infarction, nor does it react with any other human tissue antigens or blood cells.
- Antibody clone number
- Mar-48
- Concentration
- 1 mg/mL
Submitted references Huoxue Qianyang Qutan recipe attenuates Ang II-induced cardiomyocyte hypertrophy by regulating reactive oxygen species production.
Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency.
Cardiosphere-derived exosomal microRNAs for myocardial repair in pediatric dilated cardiomyopathy.
Defining the molecular signatures of human right heart failure.
Generation of multipotent induced cardiac progenitor cells from mouse fibroblasts and potency testing in ex vivo mouse embryos.
Gui M, Yao L, Lu B, Wang J, Zhou X, Li J, Dong Z, Fu D
Experimental and therapeutic medicine 2021 Dec;22(6):1446
Experimental and therapeutic medicine 2021 Dec;22(6):1446
Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency.
Jütte BB, Krollmann C, Cieslak K, Koerber RM, Boor P, Graef CM, Bartok E, Wagner M, Carell T, Landsberg J, Aymans P, Wenzel J, Brossart P, Teichmann LL
iScience 2021 Aug 20;24(8):102833
iScience 2021 Aug 20;24(8):102833
Cardiosphere-derived exosomal microRNAs for myocardial repair in pediatric dilated cardiomyopathy.
Hirai K, Ousaka D, Fukushima Y, Kondo M, Eitoku T, Shigemitsu Y, Hara M, Baba K, Iwasaki T, Kasahara S, Ohtsuki S, Oh H
Science translational medicine 2020 Dec 9;12(573)
Science translational medicine 2020 Dec 9;12(573)
Defining the molecular signatures of human right heart failure.
Williams JL, Cavus O, Loccoh EC, Adelman S, Daugherty JC, Smith SA, Canan B, Janssen PML, Koenig S, Kline CF, Mohler PJ, Bradley EA
Life sciences 2018 Mar 1;196:118-126
Life sciences 2018 Mar 1;196:118-126
Generation of multipotent induced cardiac progenitor cells from mouse fibroblasts and potency testing in ex vivo mouse embryos.
Lalit PA, Rodriguez AM, Downs KM, Kamp TJ
Nature protocols 2017 May;12(5):1029-1054
Nature protocols 2017 May;12(5):1029-1054
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- Invitrogen Antibodies (provider)
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- Experimental details
- Figure 2 HQQR improves Ang II-induced cardiomyocyte hypertrophy. (A) Immunofluorescence experiments were performed using anti-alpha-actinin antibodies to analyze cardiomyocyte hypertrophy (magnification, x200; scale bar, 50 um). (B) mRNA expression levels of the myocardial hypertrophy markers ANP, BNP and beta-MHC were examined using reverse transcription-quantitative PCR. (C) Protein expression levels of the myocardial hypertrophy markers ANP, BNP and beta-MHC were examined using western blotting. ** P
