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TAPT1
Transmembrane anterior posterior transformation 1FLJ90013
This gene encodes a highly conserved protein that localizes to the centrosome and/or ciliary basal body. Mutations in this gene disrupt Golgi morphology and trafficking and normal primary cilium formation and these mutations are congenitally manifested by severe undermineralization of the intra-uterine skeleton. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. In mouse, this gene is thought to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. [provided by RefSeq, Jan 2017]
Top validated antibodies |
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| Proteintech Group |  27657-1-AP |
1 references | Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN955076 |
2 references | Polyclonal |
WB
FC
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| OriGene | AP54151PU-N |
1 references | Polyclonal |
WB
FC
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| NovoPro Bioscience Inc. | 132481 |
Polyclonal |
WB
EL
FC
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| Invitrogen Antibodies | 27657-1-AP |
Polyclonal |
WB
IHC
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