ALG10

This gene encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel. [provided by RefSeq, Jan 2010]

Description

ALG10 alpha-1,2-glucosyltransferase

Tissue specificity

Low tissue specificity

Subcell location

Endoplasmic reticulum

Predicted location

Membrane

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted membrane proteins

Chromosome

12 (34022468 - 34029694)

Ensembl ID

ENSG00000139133  (ver. 103.38)

Orthologs

-

UniProt

Q5BKT4

neXtProt

NX_Q5BKT4

Human splice variants

Protein structure