AWAT2

This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters. [provided by RefSeq, May 2010]

Description

Acyl-CoA wax alcohol acyltransferase 2

Tissue specificity

Tissue enriched (skin)

Predicted location

Membrane

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted membrane proteins

Chromosome

X (70040542 - 70049938)

Ensembl ID

ENSG00000147160  (ver. 103.38)

Orthologs

Mouse Awat2: ENSMUSG00000031220

UniProt

Q6E213

neXtProt

NX_Q6E213

Human splice variants
Mouse splice variants

Protein structure