KRT72

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Description

Keratin 72

Tissue specificity

Group enriched (skin , testis)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

12 (52585589 - 52601538)

Ensembl ID

ENSG00000170486  (ver. 103.38)

Orthologs

Mouse Krt72: ENSMUSG00000056605

UniProt

Q14CN4

neXtProt

NX_Q14CN4

Human splice variants
Mouse splice variants

Protein structure