SMPD4

Sphingomyelin phosphodiesterase 4

FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3

The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network. [provided by RefSeq, Mar 2017]

Ensembl	UniProt	RefSeq	Entrez
ENST00000351288 ENSP00000259217	Q9NXE4.137 Q9NXE4	NP_060221.2 NP_060221	SMPD4 55627
ENST00000409031 ENSP00000386531	Q9NXE4.137 Q9NXE4	NP_060421.2 NP_060421	SMPD4 55627
ENST00000430682 ENSP00000406325	H7C2J2		SMPD4 55627
ENST00000431183 ENSP00000405187	Q9NXE4.137 Q9NXE4	NP_001164554.1 NP_001164554	SMPD4 55627
ENST00000439886 ENSP00000401648	H7C1Q6		SMPD4 55627
ENST00000441135 ENSP00000406458	C9J647		SMPD4 55627
ENST00000449159 ENSP00000403915	H7C235		SMPD4 55627
ENST00000451542 ENSP00000405363	H7C2E2		SMPD4 55627
ENST00000457039 ENSP00000397078	H7C0W5		SMPD4 55627
ENST00000680298 ENSP00000506463			SMPD4 55627
ENST00000680401 ENSP00000506367			SMPD4 55627
ENST00000680679 ENSP00000505716			SMPD4 55627

Ensembl	UniProt	RefSeq	Entrez
ENSMUST00000006053 ENSMUSP00000006053	Q6ZPR5.113 Q6ZPR5	NP_084221.2 NP_084221	Smpd4 77626
ENSMUST00000090159 ENSMUSP00000087620	Q6ZPR5.113 Q6ZPR5	NP_001158081.1 NP_001158081	Smpd4 77626
ENSMUST00000163476 ENSMUSP00000131867	Q6ZPR5.113 Q6ZPR5	NP_001158082.1 NP_001158082	Smpd4 77626
ENSMUST00000165363 ENSMUSP00000130720	Q6ZPR5.113 Q6ZPR5	NP_001158083.1 NP_001158083	Smpd4 77626
ENSMUST00000231257 ENSMUSP00000156136	A0A338P6W7		Smpd4 77626
ENSMUST00000231311 ENSMUSP00000156127	A0A338P6U9		Smpd4 77626
ENSMUST00000231436 ENSMUSP00000155897	A0A338P695		Smpd4 77626
ENSMUST00000231627 ENSMUSP00000156051	A0A338P715		Smpd4 77626
ENSMUST00000231722 ENSMUSP00000156043	A0A338P6P4		Smpd4 77626
ENSMUST00000231792 ENSMUSP00000156362	A0A338P7L1		Smpd4 77626
ENSMUST00000231887 ENSMUSP00000155917	A0A338P6E2		Smpd4 77626
ENSMUST00000232021 ENSMUSP00000156079	A0A338P6S3		Smpd4 77626
ENSMUST00000232043 ENSMUSP00000156353	A0A338P7A7		Smpd4 77626
ENSMUST00000232116 ENSMUSP00000155998	A0A338P6I0		Smpd4 77626
ENSMUST00000232271 ENSMUSP00000156215	A0A338P735		Smpd4 77626
ENSMUST00000232442 ENSMUSP00000155910	A0A338P6B0		Smpd4 77626

More gene data

Top validated antibodies
LSBio	LS-C161321		Polyclonal	WB IHC
antibodies-online	ABIN4354849		Polyclonal	WB ICC IHC
Atlas Antibodies	HPA049426	2 references	Polyclonal	ICC IHC
Novus Biologicals	NBP2-33567		Polyclonal	WB ICC IHC
NovoPro Bioscience Inc.	127872		Polyclonal	WB EL IHC

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Data in Antibodypedia (inconclusive)

Recommended by provider

88 antibodies from 21 providers.

Show Additional Columns

	Antibody	Refs	Type
LSBio 19 antibodies
	LS-C161321		Polyclonal
	LS-C151243		Polyclonal

antibodies-online 24 antibodies
	ABIN4354849		Polyclonal
	ABIN2503128		Polyclonal

Novus Biologicals 4 antibodies
	NBP2-33567		Polyclonal
	NBP2-33460		Polyclonal

Atlas Antibodies 2 antibodies
	HPA049426	2	Polyclonal
	HPA046279		Polyclonal

Biorbyt 4 antibodies
	orb313162		Polyclonal
	orb1264021		Polyclonal

Aviva Systems Biology 2 antibodies
	OAAB03304		Polyclonal
	ARP47382_P050		Polyclonal

NovoPro Bioscience Inc. 1 antibody
	127872		Polyclonal

St John's Laboratory 1 antibody
	STJ117668		Polyclonal

Abcepta 1 antibody
	AP5904a		Polyclonal

Invitrogen Antibodies 7 antibodies
	PA5-25797		Polyclonal
	PA5-143768		Polyclonal

Antibodies.com 1 antibody
	A87716		Polyclonal

GeneTex 1 antibody
	GTX120642		Polyclonal

OriGene 1 antibody
	TA342050		Polyclonal

ProSci 1 antibody
	62-097		Polyclonal

Boster Biological Technology 1 antibody
	A12855		Polyclonal

MyBioSource 1 antibody
	MBS9201087		Polyclonal

Proteintech Group 1 antibody
	14959-1-AP		Polyclonal

United States Biological 13 antibodies
	042057		Polyclonal
	042057-AP		Polyclonal

Abbexa 1 antibody
	abx032661		Polyclonal

Leading Biology 1 antibody
	APR13415G		Polyclonal

MilliporeSigma / Merck KGaA 1 antibody
	HPA049426		Polyclonal

SMPD4

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