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- References [12]
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- Product number
- NBP1-05767 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-05767, RRID:AB_1556282
- Product name
- Rabbit Polyclonal DIO3 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat, Hamster, Rabbit
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Reduced Skeletal Muscle Protein Turnover and Thyroid Hormone Metabolism in Adaptive Thermogenesis That Facilitates Body Fat Recovery During Weight Regain.
Alteration of thyroid hormone signaling triggers the diabetes-induced pathological growth, remodeling, and dedifferentiation of podocytes.
A thyroid hormone network exists in synovial fibroblasts of rheumatoid arthritis and osteoarthritis patients.
Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans.
Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding.
Mice with hepatocyte-specific deficiency of type 3 deiodinase have intact liver regeneration and accelerated recovery from nonthyroidal illness after toxin-induced hepatonecrosis.
Maternal inheritance of an inactive type III deiodinase gene allele affects mouse pancreatic β-cells and disrupts glucose homeostasis.
Thyroid hormone inactivation in gastrointestinal stromal tumors.
Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage.
A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons.
Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism.
Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells.
Calonne J, Isacco L, Miles-Chan J, Arsenijevic D, Montani JP, Guillet C, Boirie Y, Dulloo AG
Frontiers in endocrinology 2019;10:119
Frontiers in endocrinology 2019;10:119
Alteration of thyroid hormone signaling triggers the diabetes-induced pathological growth, remodeling, and dedifferentiation of podocytes.
Benedetti V, Lavecchia AM, Locatelli M, Brizi V, Corna D, Todeschini M, Novelli R, Benigni A, Zoja C, Remuzzi G, Xinaris C
JCI insight 2019 Sep 19;4(18)
JCI insight 2019 Sep 19;4(18)
A thyroid hormone network exists in synovial fibroblasts of rheumatoid arthritis and osteoarthritis patients.
Pörings AS, Lowin T, Dufner B, Grifka J, Straub RH
Scientific reports 2019 Sep 13;9(1):13235
Scientific reports 2019 Sep 13;9(1):13235
Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans.
Yamauchi I, Sakane Y, Yamashita T, Hirota K, Ueda Y, Kanai Y, Yamashita Y, Kondo E, Fujii T, Taura D, Sone M, Yasoda A, Inagaki N
Endocrine 2018 Feb;59(2):353-363
Endocrine 2018 Feb;59(2):353-363
Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding.
De Andrade PB, Neff LA, Strosova MK, Arsenijevic D, Patthey-Vuadens O, Scapozza L, Montani JP, Ruegg UT, Dulloo AG, Dorchies OM
Frontiers in physiology 2015;6:254
Frontiers in physiology 2015;6:254
Mice with hepatocyte-specific deficiency of type 3 deiodinase have intact liver regeneration and accelerated recovery from nonthyroidal illness after toxin-induced hepatonecrosis.
Castroneves LA, Jugo RH, Maynard MA, Lee JS, Wassner AJ, Dorfman D, Bronson RT, Ukomadu C, Agoston AT, Ding L, Luongo C, Guo C, Song H, Demchev V, Lee NY, Feldman HA, Vella KR, Peake RW, Hartigan C, Kellogg MD, Desai A, Salvatore D, Dentice M, Huang SA
Endocrinology 2014 Oct;155(10):4061-8
Endocrinology 2014 Oct;155(10):4061-8
Maternal inheritance of an inactive type III deiodinase gene allele affects mouse pancreatic β-cells and disrupts glucose homeostasis.
Medina MC, Fonesca TL, Molina J, Fachado A, Castillo M, Dong L, Soares R, Hernández A, Caicedo A, Bianco AC
Endocrinology 2014 Aug;155(8):3160-71
Endocrinology 2014 Aug;155(8):3160-71
Thyroid hormone inactivation in gastrointestinal stromal tumors.
Maynard MA, Marino-Enriquez A, Fletcher JA, Dorfman DM, Raut CP, Yassa L, Guo C, Wang Y, Dorfman C, Feldman HA, Frates MC, Song H, Jugo RH, Taguchi T, Hershman JM, Larsen PR, Huang SA
The New England journal of medicine 2014 Apr 3;370(14):1327-34
The New England journal of medicine 2014 Apr 3;370(14):1327-34
Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage.
Vose LR, Vinukonda G, Jo S, Miry O, Diamond D, Korumilli R, Arshad A, Zia MT, Hu F, Kayton RJ, La Gamma EF, Bansal R, Bianco AC, Ballabh P
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Oct 30;33(44):17232-46
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Oct 30;33(44):17232-46
A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons.
Kalló I, Mohácsik P, Vida B, Zeöld A, Bardóczi Z, Zavacki AM, Farkas E, Kádár A, Hrabovszky E, Arrojo E Drigo R, Dong L, Barna L, Palkovits M, Borsay BA, Herczeg L, Lechan RM, Bianco AC, Liposits Z, Fekete C, Gereben B
PloS one 2012;7(6):e37860
PloS one 2012;7(6):e37860
Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism.
Jo S, Kalló I, Bardóczi Z, Arrojo e Drigo R, Zeöld A, Liposits Z, Oliva A, Lemmon VP, Bixby JL, Gereben B, Bianco AC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Jun 20;32(25):8491-500
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Jun 20;32(25):8491-500
Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells.
Freitas BC, Gereben B, Castillo M, Kalló I, Zeöld A, Egri P, Liposits Z, Zavacki AM, Maciel RM, Jo S, Singru P, Sanchez E, Lechan RM, Bianco AC
The Journal of clinical investigation 2010 Jun;120(6):2206-17
The Journal of clinical investigation 2010 Jun;120(6):2206-17
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DIO3 Antibody [NBP1-05767] - Detection of Dio3 in rabbit brain whole cell homogenate. Photo courtesy of product review by verified customer.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DIO3 Antibody [NBP1-05767] - Detection of Dio3 in rat placenta.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: DIO3 Antibody [NBP1-05767] - Analysis using the Biotin conjugate of NBP1-05767. Dio3 staining of mouse hepatic stellate cell cultured for 7 days. Image from verified customer review.
