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- References [9]
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- Product number
- ABIN446386 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 250-300), (Internal Region) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat, Hamster, Rabbit
- Host
- Rabbit
- Epitope
- AA 250-300, Internal Region
- Vial size
- 0.025 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans.
Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding.
Mice with hepatocyte-specific deficiency of type 3 deiodinase have intact liver regeneration and accelerated recovery from nonthyroidal illness after toxin-induced hepatonecrosis.
Maternal inheritance of an inactive type III deiodinase gene allele affects mouse pancreatic β-cells and disrupts glucose homeostasis.
Thyroid hormone inactivation in gastrointestinal stromal tumors.
Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage.
A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons.
Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism.
Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells.
Yamauchi I, Sakane Y, Yamashita T, Hirota K, Ueda Y, Kanai Y, Yamashita Y, Kondo E, Fujii T, Taura D, Sone M, Yasoda A, Inagaki N
Endocrine 2018 Feb;59(2):353-363
Endocrine 2018 Feb;59(2):353-363
Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding.
De Andrade PB, Neff LA, Strosova MK, Arsenijevic D, Patthey-Vuadens O, Scapozza L, Montani JP, Ruegg UT, Dulloo AG, Dorchies OM
Frontiers in physiology 2015;6:254
Frontiers in physiology 2015;6:254
Mice with hepatocyte-specific deficiency of type 3 deiodinase have intact liver regeneration and accelerated recovery from nonthyroidal illness after toxin-induced hepatonecrosis.
Castroneves LA, Jugo RH, Maynard MA, Lee JS, Wassner AJ, Dorfman D, Bronson RT, Ukomadu C, Agoston AT, Ding L, Luongo C, Guo C, Song H, Demchev V, Lee NY, Feldman HA, Vella KR, Peake RW, Hartigan C, Kellogg MD, Desai A, Salvatore D, Dentice M, Huang SA
Endocrinology 2014 Oct;155(10):4061-8
Endocrinology 2014 Oct;155(10):4061-8
Maternal inheritance of an inactive type III deiodinase gene allele affects mouse pancreatic β-cells and disrupts glucose homeostasis.
Medina MC, Fonesca TL, Molina J, Fachado A, Castillo M, Dong L, Soares R, Hernández A, Caicedo A, Bianco AC
Endocrinology 2014 Aug;155(8):3160-71
Endocrinology 2014 Aug;155(8):3160-71
Thyroid hormone inactivation in gastrointestinal stromal tumors.
Maynard MA, Marino-Enriquez A, Fletcher JA, Dorfman DM, Raut CP, Yassa L, Guo C, Wang Y, Dorfman C, Feldman HA, Frates MC, Song H, Jugo RH, Taguchi T, Hershman JM, Larsen PR, Huang SA
The New England journal of medicine 2014 Apr 3;370(14):1327-34
The New England journal of medicine 2014 Apr 3;370(14):1327-34
Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage.
Vose LR, Vinukonda G, Jo S, Miry O, Diamond D, Korumilli R, Arshad A, Zia MT, Hu F, Kayton RJ, La Gamma EF, Bansal R, Bianco AC, Ballabh P
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Oct 30;33(44):17232-46
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Oct 30;33(44):17232-46
A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons.
Kalló I, Mohácsik P, Vida B, Zeöld A, Bardóczi Z, Zavacki AM, Farkas E, Kádár A, Hrabovszky E, Arrojo E Drigo R, Dong L, Barna L, Palkovits M, Borsay BA, Herczeg L, Lechan RM, Bianco AC, Liposits Z, Fekete C, Gereben B
PloS one 2012;7(6):e37860
PloS one 2012;7(6):e37860
Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism.
Jo S, Kalló I, Bardóczi Z, Arrojo e Drigo R, Zeöld A, Liposits Z, Oliva A, Lemmon VP, Bixby JL, Gereben B, Bianco AC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Jun 20;32(25):8491-500
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Jun 20;32(25):8491-500
Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells.
Freitas BC, Gereben B, Castillo M, Kalló I, Zeöld A, Egri P, Liposits Z, Zavacki AM, Maciel RM, Jo S, Singru P, Sanchez E, Lechan RM, Bianco AC
The Journal of clinical investigation 2010 Jun;120(6):2206-17
The Journal of clinical investigation 2010 Jun;120(6):2206-17
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS
