FNab02101

antibody from FineTest Biotech

Targeting: CXCR3 CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

FNab02101

Provider

FineTest Biotech

Product name

CXCR3B-specific antibody

Antibody type

Monoclonal

Antigen

Recombinant protein fragment

Description

CXCR3(C-X-C chemokine receptor type 3) is a G protein-coupled, seven-transmembrane domain chemokine receptor that is expressed on the surface of a number of cell types, including activated CD4+ and CD8+ T cells, NK and NK-T cells, plasmacytoid dendritic cells, and some B cells(PMID: 16847335). CXCR3 binds and is activated by the three IFN-gamma-inducible chemokines: CXCL9, CXCL10, and CXCL11. Binding of these ligands to CXCR3 has been implicated in regulating T-cell infiltration during inflammation and tissue injury(PMID: 17250586). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms, CXCR3B, mediates the angiostatic activity of CXCR3 ligands and also acts as functional receptor for CXCL4(PMID:12782716). This monoclonal antibody is specific to CXCR3B.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

chemokine(C-X-C motif) receptor 3


Epitope

IgG1

Isotype

IgG

Antibody clone number

6F7

Vial size

100¦Ìg

Concentration

Protein A+G purification

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

Handling

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)