TM2D2

The protein encoded by this gene contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. This gene has multiple alternatively spliced transcript variants which encode two different isoforms. [provided by RefSeq, Jul 2008]

Description

TM2 domain containing 2

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Vesicles, Plasma membrane

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

8 (38988808 - 38996824)

Ensembl ID

ENSG00000169490  (ver. 103.38)

Orthologs

Mouse Tm2d2: ENSMUSG00000031556

UniProt

Q9BX73

neXtProt

NX_Q9BX73

Human splice variants
Mouse splice variants

Protein structure