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LearnPAB1700
antibody from Abnova Corporation
Targeting: UBQLN2
Chap1, CHAP1/DSK2, Dsk2, LIC-2, N4BP4, PLIC-2, PLIC2, RIHFB2157
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- PAB1700 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB1700, RRID:AB_1238050
- Product name
- UBQLN2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of UBQLN2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Ubiquilin-2 (UBQLN2) binds with high affinity to the C-terminal region of TDP-43 and modulates TDP-43 levels in H4 cells: characterization of inhibition by nucleic acids and 4-aminoquinolines.
Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a.
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.
Selection system for genes encoding nuclear-targeted proteins.
Cassel JA, Reitz AB
Biochimica et biophysica acta 2013 Jun;1834(6):964-71
Biochimica et biophysica acta 2013 Jun;1834(6):964-71
Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a.
Walters KJ, Kleijnen MF, Goh AM, Wagner G, Howley PM
Biochemistry 2002 Feb 12;41(6):1767-77
Biochemistry 2002 Feb 12;41(6):1767-77
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.
Kleijnen MF, Shih AH, Zhou P, Kumar S, Soccio RE, Kedersha NL, Gill G, Howley PM
Molecular cell 2000 Aug;6(2):409-19
Molecular cell 2000 Aug;6(2):409-19
Selection system for genes encoding nuclear-targeted proteins.
Ueki N, Oda T, Kondo M, Yano K, Noguchi T, Muramatsu M
Nature biotechnology 1998 Dec;16(13):1338-42
Nature biotechnology 1998 Dec;16(13):1338-42
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The UBQLN2 polyclonal antibody (Cat # PAB1700) is used in Western blot to detect UBQLN2 in HeLa cell lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with UBQLN2 polyclonal antibody (Cat # PAB1700) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with UBQLN2 polyclonal antibody (Cat # PAB1700) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
