CABT-BL3733

antibody from Creative Diagnostics

Targeting: ULBP3 RAET1N

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-BL3733

Provider

Creative Diagnostics

Product name

Anti-ULBP3 monoclonal antibody, clone NN0605-7F23

Antibody type

Monoclonal

Description

ULBP3 is a human ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. ULBP3 has a lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

NN0605-7F23

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.