BS2876

antibody from Bioworld Technology, Inc
Targeting: RNASE3 ECP, RAF1, RNS3
Provider product page for BS2876

Antibody data

Product number
BS2876 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ECP (V151) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 130-170 of Human ECP.
Description
ECP (eosinophil cationic protein), also known as RNS3 or RNASE3 (ribonuclease,RNase A family, 3), is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family. ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system. ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils. ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities. It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis and tremor that may lead to death. ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RNASE3 protein structure - BS2876 shown in red.