Tissue expression
Cell line expression
Protein structure
MT1A
Metallothionein 1AMT1, MT1S
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. [provided by RefSeq, Sep 2017]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
2 references | Monoclonal |
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Antibodies.com | ![]() |
Monoclonal |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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Cusabio Biotech Co., Ltd | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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