Tissue expression
Cell line expression
Protein structure
SRY
Sex determining region YTDF
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ![]() |
2 references | Monoclonal |
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GeneTex | ![]() |
Monoclonal |
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Novus Biologicals | ![]() |
Monoclonal |
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Proteintech Group | ![]() |
Polyclonal |
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Affinity Biosciences | ![]() |
Monoclonal |
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