FNab00479

antibody from FineTest Biotech

Targeting: APEX1 APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

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Validation data

Product number: FNab00479 - Provider product page
Provider: FineTest Biotech
Product name: APEX1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: APEX nuclease (multifunctional DNA repair enzyme) 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)

APEX1 protein structure - FNab00479 shown in red.