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Protein structure
CXCL1
C-X-C motif chemokine ligand 1FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-86508 |
4 references | Polyclonal |
WB
ICC
IHC
OA
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| R&D Systems | MAB275-100 |
11 references | Monoclonal |
WB
EL
FC
BN
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| Proteintech Group | 12335-1-AP |
26 references | Polyclonal |
WB
EL
IHC
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| Novus Biologicals | AF-515-NA |
2 references | Polyclonal |
WB
IHC
BN
|
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| OriGene | PP1080P1 |
Polyclonal |
WB
EL
IHC
FA
|
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