1191-MSM11-P0

antibody from Invitrogen Antibodies

Targeting: CLU APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2

Antibody data

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Validation data

Product number: 1191-MSM11-P0 - Provider product page
Provider: Invitrogen Antibodies
Product name: Clusterin/Apolipoprotein J (APO-J) Monoclonal Antibody (CLU, 4731)
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
Reactivity: Human
Host: Mouse
Isotype: IgG
Antibody clone number: CLU, 4731
Vial size: 20 µg
Concentration: 200 µg/mL
Storage: 4° C

CLU protein structure - 1191-MSM11-P0 shown in red.

Supportive validation

Submitted by: Invitrogen Antibodies (provider)
Main image
Experimental details: Analysis of Protein Array containing more than 19,000 full-length human proteins Clusterin, Apolipoprotein J (APO-J) Monoclonal Antibody (Product # 1191-MSM11-P1). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Supportive validation

Submitted by: Invitrogen Antibodies (provider)
Main image
Experimental details: Analysis of Protein Array containing more than 19,000 full-length human proteins Clusterin, Apolipoprotein J (APO-J) Monoclonal Antibody (Product # 1191-MSM11-P1). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.