Tissue expression
Cell line expression
Protein structure
MUC21
Mucin 21, cell surface associatedbCX31G15.2, C6orf205
This gene encodes a large membrane-bound glycoprotein which is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. The encoded protein contains an N-terminal signal sequence, an extracellular mucin domain, a stem domain, a transmembrane domain, and a C-terminal cytoplasmic tail domain. The mucin domain contains O-glycosylation sites and is polymorphic with isoforms containing a variable number of nonidentical proline-, threonine-, and serine-rich tandem repeats of 15 amino acids each. The aberrent expression of this gene is associated with lung adenocarcinoma. [provided by RefSeq, May 2017]
Top validated antibodies |
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Atlas Antibodies | HPA052028 | Polyclonal |
IHC
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antibodies-online | ABIN4336539 | Polyclonal |
ICC
IHC |
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Biorbyt | orb863854 | Polyclonal |
WB
EL |
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Novus Biologicals | NBP2-31023 | Polyclonal |
IHC
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Invitrogen Antibodies | PA5-62536 | Polyclonal |
IHC
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