BS7828

antibody from Bioworld Technology, Inc
Targeting: DAPK1 DAPK, ROCO3
Provider product page for BS7828
Western blot
Immunohistochemistry

Antibody data

Product number
BS7828 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DAPK1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human DAPK1.
Description
DAP (death associated protein) kinase and ZIP kinase are members of a novel protein kinase family, the members of which have the capacity to mediate apoptosis through their catalytic activities. DAP kinase (DAPK) contains a ¡ùdeath domain¡ì and has been shown to mediate IFN-ÎÛ-induced apoptosis. The introduction of DAPK into highly metastatic carcinoma clones lacking DAPK expression has been shown to result in the suppression of metastasis, thus linking suppression of apoptosis to metastasis. ZIP kinase contains a leucine zipper domain, which is necessary for homodimerization and for interaction with other leucine zipper proteins. ZIP kinase dimerizes with ATF-4, an ATF/CREB transcription factor family member that contains a leucine zipper. Overexpression of ZIP kinase has been shown to result in morphological changes associated with apoptosis in NIH/3T3 cells.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DAPK1 protein structure - BS7828 shown in red.