PAB1878

antibody from Abnova Corporation

Targeting: PDE8A HsT19550

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB1878

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB1878, RRID:AB_1578525

Product name

PDE8A polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of PDE8A.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Per-Arnt-Sim domain-dependent association of cAMP-phosphodiesterase 8A1 with IkappaB proteins.

Wu P, Wang P
Proceedings of the National Academy of Sciences of the United States of America 2004 Dec 21;101(51):17634-9

---

Comparison of enzymatic characterization and gene organization of cyclic nucleotide phosphodiesterase 8 family in humans.

Gamanuma M, Yuasa K, Sasaki T, Sakurai N, Kotera J, Omori K
Cellular signalling 2003 Jun;15(6):565-74

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of PDE8A polyclonal antibody (Cat # PAB1878) in HL-60 cell line lysates (35 ug/lane). PDE8A (arrow) was detected using the purified polyclonal antibody.

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PDE8A polyclonal antibody (Cat # PAB1878) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)