NOMO3

This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a duplicated region on the short arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum. [provided by RefSeq, Jul 2008]

Description

NODAL modulator 3

Tissue specificity

Tissue enhanced (pancreas)

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins

Chromosome

16 (16232506 - 16300806)

Ensembl ID

ENSG00000103226  (ver. 103.38)

Orthologs

-

UniProt

P69849

neXtProt

NX_P69849

Human splice variants

Protein structure